Biased visualization of hypoperfused tissue by computed tomography due to short imaging duration: improved classification by image down-sampling and vascular models.
Mikkelsen IK, Jones PS, Ribe LR, et al. Eur Radiol. 2015;25(7):2080-2088
Lesion detection in acute stroke by computed-tomography perfusion (CTP) can be affected by incomplete bolus coverage in veins and hypoperfused tissue, so-called bolus truncation (BT), and low contrast-to-noise ratio (CNR). We examined the BT-frequency and hypothesized that image down-sampling and a vascular model (VM) for perfusion calculation would improve normo- and hypoperfused tissue classification.
BT is not uncommon in stroke CTP with 40-s scan duration. Applying image down-sampling and VM improve tissue classification.
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