Webinar 🇺🇸

Next-Generation Perfusion Imaging in the Study of Neurodegenerative Disease Pathophysiology.

How can changes in the brain’s capillary network affect blood flow and oxygenation - and what can advanced imaging reveal about the earliest stages of neurodegenerative disease?

Building on the previous webinar session (held 17 Sept 2025), this webinar will examine how capillary changes in healthy individuals may influence cerebral blood flow and contribute to the maintenance of brain oxygenation. We will also discuss how next-generation perfusion imaging can be used to investigate early pathophysiological changes in individuals at risk of Alzheimer’s disease (AD) and Parkinson’s disease (PD).

>>> Watch the Replay Here: Perfusion Imaging in Cerebral Small Vessel Disease and Alzheimer's Disease

Event Information:

Date: 12 November 2026, Thursday
Time: 12:00-13:00 ET
18:00-19:00 CEST (UTC+2)
Language: English

Presenter:

Prof. Leif Østergaard
MSc, MD, PhD, DMSc, Dept. of Radiology
Aarhus University, Denmark

Prof. Leif Østergaard is a leading expert in brain perfusion and imaging at Aarhus University. He has pioneered advanced MRI techniques that support clinicians in understanding and managing conditions such as stroke and dementia. With research experience from Harvard Medical School, he has authored more than 175 scientific publications and was awarded the prestigious Danish Lassen Prize in recognition of his contributions to brain research.

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CLINICAL USE CASES AND TECHNICAL HIGHLIGHTS

CLINICAL USE CASES

Directly impacts the patient treatment pathway, both intra- and post-intervention.
Assess outcomes post-intervention: detect missed stenoses, distal occlusions, or microvascular disturbances.
Guide complementary therapies on the spot based on perfusion status.
May detect the no-reflow phenomenon — providing insight into cases where recovery may fail despite successful thrombectomy.
Potentially enables direct-to-angio workflows.

TECHNICAL HIGHLIGHTS

Full set of perfusion markers: CBF, CBV, MTT.
Advanced oxygen metabolism imaging: OEF, CMRO₂.
Most reliable results with 10 CBCT acquisitions.
Vendor-agnostic platform.

CBCT Imaging

Side-by-side comparison: The left-hand side is the raw CBCT data, while the right-hand side panel is the pre-processed data.

Using CMN software in the angio suite delivers results comparable to conventional CT/MR perfusion.

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